Your fastest option
At a pharmacy
- How it's dispensed
- Medicaid
- Typical cost
Updated regularly · All 50 states
Pick your state to see the fastest way to get it, what it costs, where to go, and what the law actually protects.
If someone is overdosing right now
Say "I think this is an opioid overdose." Stay on the line. The Good Samaritan law in almost every state protects you — you can see yours above.
Tilt their head back. Insert the nozzle. Press the plunger all the way down. That is the full dose — do not prime it first.
Use the other nostril. Fentanyl overdoses often need two doses. It's safe to give more.
This is the recovery position. It keeps their airway clear. Stay until paramedics arrive.
Naloxone cannot hurt someone who isn't on opioids. If you are unsure, give it anyway.
About naloxone
Naloxone — often sold as Narcan — is a nasal spray that reverses an opioid overdose within minutes. It works on heroin, fentanyl, oxycodone, methadone, and every other opioid. It does nothing to people who don't have opioids in their system, which is why it's safe to carry and safe to use when you aren't sure.
In 2023 the FDA made it available over the counter. You do not need a prescription, an ID, or a reason. You do not need to explain yourself at the pharmacy counter. One box holds two doses.
Carrying naloxone is not a sign that something is wrong in your life. It is the same reason people learn CPR: because the minutes before an ambulance arrives are the minutes that matter.
What it costs
Common questions
No. Naloxone nasal spray is over the counter at every major pharmacy chain.
Almost certainly not. Every state except Kansas and South Dakota has a Good Samaritan law. The details vary — select your state above to see exactly what's protected.
Yes. Fentanyl is stronger, so strong overdoses sometimes need a second dose two to three minutes after the first. Call 911 first, give naloxone, give another if they don't respond.
Nothing happens. Naloxone only affects opioids. If they aren't on opioids, it will not hurt them.
Yes, but most states' Good Samaritan laws protect you even if you use expired naloxone. Expired naloxone is still better than no naloxone.
Yes, if you can. Most overdoses happen in front of someone who isn't using. Keep one kit at home and one in your bag. Teach the people you live with.
Your fastest option